Recombinant Human Anti-NPNA Antibody (PfNPNA-1) (CAT#: FAMAB-0225-CN)
The fully human monoclonal antibody PfNPNA-1 against (NPNA)3 specifically labels Plasmodium falciparum in an IFA. PfNPNA-1 is a promising candidate for evaluation for the prevention of malaria.
Specific Inquiry
IF
Figure 1 Indirect immunofluorescence assay (IFA) on Plasmo-dium falciparum sporozoites.
Anti-sporozoite activity of the PfNPNA-1 VH/κ moleculewas clearly evident in an immunofluorescence assay (IFA) with P. falciparum sporozoites.
Chappel, J. A., Rogers, W. O., Hoffman, S. L., & Kang, A. S. (2004). Molecular dissection of the human antibody response to the structural repeat epitope of Plasmodium falciparum sporozoite from a protected donor. Malaria journal, 3(1), 28.
ELISA
Figure 2 Competition ELISA was carried out to approximate the affinity of binding.
Binding affinity ofthe monovalent PfNPNA-1 for (NPNA)3 comparedfavourably with values previously reported for a panel ofconventional murine monoclonal antibodies directedagainst the repeat epitope, which also have affinitiesin the µM range.
Chappel, J. A., Rogers, W. O., Hoffman, S. L., & Kang, A. S. (2004). Molecular dissection of the human antibody response to the structural repeat epitope of Plasmodium falciparum sporozoite from a protected donor. Malaria journal, 3(1), 28.
Specifications
- Host Species
- Human
- Type
- Human IgG4
- Specificity
- Plasmodium falciparum NPNA
- Species Reactivity
- Plasmodium falciparum
- Clone
- PfNPNA-1
- Applications
- ELISA, IF
- Related Disease
- Malaria
Product Property
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay and Immunofluorescence.
Target
- Alternative Names
- NPNA
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone PfNPNA-1"
See other products for "NPNA"
Select a product category from the dropdown menu below to view related products.
Please select product type
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0225-CN-S(P) | Recombinant Human Anti-NPNA Antibody scFv Fragment (PfNPNA-1) | ELISA, IF | Human scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for FAMAB-0225-CN. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
-1.jpg)
Application: IB, ELISA, FC, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA
Application: WB, ELISA, FC, IHC, IF, IP
Application: ELISA, IHC, IF, IP, FC, FuncS
Application: ELISA, Neut, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
