Mouse Anti-PLXNA1 Recombinant Antibody (clone 8A10A6)
CAT#: VS7-0425-WR635
This product is a mouse IgG1 antibody that binds to human PLXNA1. The antibody 8A10A6 recognizes specific amino acid domain of human PLXNA1 (AA: 1100-1200). It can be used for ICC and FC assays.
Specifications
- Immunogen
- Recombinant human PLXNA1 (AA: 1100-1200) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human PLXNA1
- Species Reactivity
- Human
- Clone
- 8A10A6
- Molecule Class
- Transmembrane Protein
- Applications
- ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Dworschak-Punetha neurodevelopmental syndrome (DWOPNED)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- NOV; NOVP; PLXN1; DWOPNED; PLEXIN-A1
- Gene ID
- 5361
- UniProt ID
- Q9UIW2
- Long Name
- Plexin A1
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Disulfide bond; Glycoprotein
- Protein Refseq
- NP_115618.3
- Function
- Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. Acts as coreceptor of TREM2 for SEMA6D in dendritic cells and is involved in the generation of immune responses and skeletal homeostasis.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
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Secondary Antibody
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Reconstitution Buffer
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Recommended Dilution Buffer
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- Product Name
See other products for "PLXNA1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2759 | Hi-Affi™ Recombinant Rabbit Anti-PLXNA1 Monoclonal Antibody (DS2759AB) | FC, ICC, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2524LY-F(E) | Mouse Anti-PLXNA1 Recombinant Antibody; Fab Fragment (HPAB-2524LY-F(E)) | ELISA | Mouse Fab |
| HPAB-2525LY-F(E) | Mouse Anti-PLXNA1 Recombinant Antibody; Fab Fragment (HPAB-2525LY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2524LY | Mouse Anti-PLXNA1 Recombinant Antibody (HPAB-2524LY) | ELISA | Mouse IgG |
| HPAB-2525LY | Mouse Anti-PLXNA1 Recombinant Antibody (HPAB-2525LY) | ELISA | Mouse IgG |
| VS3-WK671 | Rabbit Anti-PLXNA1 Recombinant Antibody (clone JU50-37) | WB, ELISA | Rabbit IgG |
| VS3-XY3468 | Rabbit Anti-PLXNA1 Recombinant Antibody (clone R08-2J4) | WB, ICC, IF, FC | Rabbit IgG |
| VS7-0425-WR636 | Mouse Anti-PLXNA1 Recombinant Antibody (clone 7B8H9) | FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2524LY-S(P) | Mouse Anti-PLXNA1 Recombinant Antibody; scFv Fragment (HPAB-2524LY-S(P)) | ELISA | Mouse scFv |
| HPAB-2525LY-S(P) | Mouse Anti-PLXNA1 Recombinant Antibody; scFv Fragment (HPAB-2525LY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC505 | Recombinant Anti-PLXNA1 Vesicular Antibody, EV Displayed (VS-0425-YC505) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5504 | Anti-PLXNA1 Immunohistochemistry Kit | IHC |
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