Rabbit Anti-PRKCG Recombinant Antibody (clone R06-8C6) (CAT#: VS3-FY1835)
This R06-8C6 recombinant monoclonal antibody has the ability to specifically bind to human PRKCG. It cross-reacts with rat. It is suitable for use in a variety of assays, including WB, IP. Applications Tested: The PKC gamma antibody has been tested by western blot analysis of PKC gamma in rat brain lysates.
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WB
Figure 1 Anti-PRKCG Antibody (VS3-FY1835) in WB.
The PKC gamma expression in rat brain lysates were detected using the anti-PKC gamma by western blot assay.
Specifications
- Immunogen
- Recombinant human PKC protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat PRKCG
- Species Reactivity
- Human, Rat
- Clone
- R06-8C6
- Applications
- Western Blot, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 78 kDa, while the observed molecular weight stands at 78 kDa.
- Related Disease
- Spinocerebellar Ataxia 14 and Hereditary Ataxia
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- PKCG; SCA14
- Gene ID
- 5582
- UniProt ID
- P05129
- Sequence Similarities
- Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
- Cellular Localization
- Cell membrane, Cell projection, Cytoplasm, Membrane, Synapse, Synaptosome
- Post Translation Modifications
- Autophosphorylation on Thr-674 appears to regulate motor functions of junctophilins, JPH3 and JPH4. (P05129-KPCG_HUMAN)
Ubiquitinated. (P05129-KPCG_HUMAN)
Modification sites at PhosphoSitePlus (P05129)
Modification sites at neXtProt (NX_P05129)
- Protein Refseq
- XP_047295048.1; XP_054177413.1; NP_001303258.1; NP_002730.1
- Function
- Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3038z | Mouse Anti-PRKCG Recombinant Antibody (clone 5G8) | WB, ELISA, ICC, IP | Mouse IgG1 |
| MRO-1240-CN | Recombinant Rabbit Anti-PRKCG Monoclonal Antibody (JG69-32) | WB, IHC | Rabbit IgG |
| ZG-0415U | Rabbit Anti-PRKCG Recombinant Antibody (clone K21-L), FITC | FC | Rabbit IgG |
| VS3-FY1194 | Recombinant Rabbit Anti-PRKCG (phospho Thr514) Antibody (clone R02-4F3) | WB, IHC-P, IP | Rabbit IgG |
| VS3-FY1195 | Recombinant Rabbit Anti-PRKCG (phospho Thr410) Antibody (clone R03-3D0) | WB, IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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