Rabbit Anti-PRKCG Recombinant Antibody (clone R06-8C6)

CAT#: VS3-FY1835

This R06-8C6 recombinant monoclonal antibody has the ability to specifically bind to human PRKCG. It cross-reacts with rat. It is suitable for use in a variety of assays, including WB, IP. Applications Tested: The PKC gamma antibody has been tested by western blot analysis of PKC gamma in rat brain lysates.

Tested Data
Figure 1 Anti-PRKCG Antibody (VS3-FY1835) in WB.

Specifications

  • Immunogen
  • Recombinant human PKC protein
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human and Rat PRKCG
  • Species Reactivity
  • Human, Rat
  • Clone
  • R06-8C6
  • Applications
  • Western Blot, Immunoprecipitation
  • MW
  • The calculated weight of the target protein is approximately 78 kDa, while the observed molecular weight stands at 78 kDa.
  • Related Disease
  • Spinocerebellar Ataxia 14 and Hereditary Ataxia

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunoprecipitation: 1/20

Target

  • Alternative Names
  • PKCG; SCA14
  • Sequence Similarities
  • Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
  • Cellular Localization
  • Cell membrane, Cell projection, Cytoplasm, Membrane, Synapse, Synaptosome
  • Post Translation Modifications
  • Autophosphorylation on Thr-674 appears to regulate motor functions of junctophilins, JPH3 and JPH4. (P05129-KPCG_HUMAN)
    Ubiquitinated. (P05129-KPCG_HUMAN)
    Modification sites at PhosphoSitePlus (P05129)
    Modification sites at neXtProt (NX_P05129)
  • Function
  • Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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Secondary Antibody

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MOR-2857 Hi-Affi™ Recombinant Rabbit Anti-PRKCG Monoclonal Antibody (DS2857AB) WB, IP, IHC-P, ICC, IF IgG
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VS-0525-XY5696 Anti-PRKCG Immunohistochemistry Kit IHC
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