Human Anti-S. aureus LTA Recombinant Antibody (clone S3) (CAT#: FAMAB-0020JF)
Recombinant monoclonal antibody S3 specially binds to Staphylococcus aureus LTA. This human anti-Staphylococcus aureus antibody S3 can be potentially used in treating S. aureus infections.
Specific Inquiry
ELISA
Figure 1 S. aureus-induced hBD-3 gene expression is TLR2 dependent.
The data shown are representative of two independent experiments performed in quadruplicate and are expressed relative to the values measured in the IgG2a-treated controls.
Menzies, B. E., & Kenoyer, A. (2006). Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human β-defensin 3 in skin keratinocytes. Infection and immunity, 74(12), 6847-6854.
WB
Figure 2 Activation of p38 MAPK in epidermal keratinocytes was examined in cell lysates collected at various times after stimulation with either viable S. aureus (MOI of 50) or LTA (5 g/ml) and screened by Western blotting
Role of p38 activation in S. aureus-induced hBD-3 gene upregulation.
Menzies, B. E., & Kenoyer, A. (2006). Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human β-defensin 3 in skin keratinocytes. Infection and immunity, 74(12), 6847-6854.
IF
Figure 3 Immunofluorescence staining of hBD-3 in S. aureus-stimulated keratinocytes pretreated with the p38 inhibitor SB203580 (50 M) for 60 min prior to and during stimulation with viable S. aureus.
The mean O.D. values and standard deviations for the nine mice in each group are shown.
Menzies, B. E., & Kenoyer, A. (2006). Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human β-defensin 3 in skin keratinocytes. Infection and immunity, 74(12), 6847-6854.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Staphylococcus aureus LTA
- Species Reactivity
- S. aureus
- Clone
- S3
- Applications
- WB, ELISA, IF
- Related Disease
- Staphylococcus aureus infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The S. aureus LTA antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunofluorescence.
Target
- Alternative Names
- lipoteichoic acid
- Function
- Enhancing phagecytosis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1033WJ | Human Anti-S. aureus LTA Recombinant Antibody (HPAB-1033WJ) | ELISA | Human IgG |
| HPAB-S0092-YC | Human Anti-S. aureus LTA Recombinant Antibody (clone A110) | ELISA, FuncS | Chimeric (mouse/human) IgG |
| HPAB-S0093-YC | Human Anti-S. aureus LTA Recombinant Antibody (clone A120a) | ELISA, FuncS | Chimeric (mouse/human) IgG |
| HPAB-S0094-YC | Human Anti-S. aureus LTA Recombinant Antibody (clone A120b) | ELISA, FuncS | Chimeric (mouse/human) IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1033WJ-S(P) | Human Anti-S. aureus LTA Recombinant Antibody; scFv Fragment (HPAB-1033WJ-S(P)) | ELISA | Human scFv |
| HPAB-S0092-YC-S(P) | Human Anti-S. aureus LTA Recombinant Antibody (clone A110); scFv Fragment | ELISA, FuncS | Mouse scFv |
| HPAB-S0093-YC-S(P) | Human Anti-S. aureus LTA Recombinant Antibody (clone A120a); scFv Fragment | ELISA, FuncS | Mouse scFv |
| HPAB-S0094-YC-S(P) | Human Anti-S. aureus LTA Recombinant Antibody (clone A120b); scFv Fragment | ELISA, FuncS | Mouse scFv |
| FAMAB-0020JF-S(P) | Human Anti-S. aureus LTA Recombinant Antibody (clone S3); scFv Fragment | WB, ELISA, FuncS | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1033WJ-F(E) | Human Anti-S. aureus LTA Recombinant Antibody; Fab Fragment (HPAB-1033WJ-F(E)) | ELISA | Human Fab |
| HPAB-S0092-YC-F(E) | Human Anti-S. aureus LTA Recombinant Antibody (clone A110); Fab Fragment | ELISA, FuncS | Chimeric (mouse/human) Fab |
| HPAB-S0093-YC-F(E) | Human Anti-S. aureus LTA Recombinant Antibody (clone A120a); Fab Fragment | ELISA, FuncS | Chimeric (mouse/human) Fab |
| HPAB-S0094-YC-F(E) | Human Anti-S. aureus LTA Recombinant Antibody (clone A120b); Fab Fragment | ELISA, FuncS | Chimeric (mouse/human) Fab |
| FAMAB-0020JF-F(E) | Human Anti-S. aureus LTA Recombinant Antibody (clone S3); Fab Fragment | WB, ELISA, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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