Human Anti-SIGLEC15 Recombinant Antibody (clone h24A3-H2/L2) (CAT#: HPAB-AP452-YC)
Provided is an antibody which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53509/1201_B2_5_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53509/1201_B2_5_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000197046-SIGLEC15/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000197046-SIGLEC15/subcellular
Specifications
- Immunogen
- Purified soluble human Siglec-15 extracellular domain
- Host Species
- Human
- Derivation
- Humanized (rat/human)
- Type
- Humanized (rat/human) IgG2
- Specificity
- Human SIGLEC15
- Species Reactivity
- Human
- Clone
- h24A3-H2/L2
- Applications
- Inhib, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Sialic Acid Binding Ig Like Lectin 15; CD33 Antigen-Like 3; CD33 Molecule-Like 3; SIGLEC-15; CD33L3; Sialic Acid Binding Ig-Like Lectin 15; Sialic Acid-Binding Ig-Like Lectin 15; HsT1361
- Gene ID
- 284266
- UniProt ID
- Q6ZMC9
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-568CL | Human Anti-SIGLEC15 Recombinant Antibody (TAB-568CL) | ELISA | Human IgG2 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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