Mouse Anti-TNP Recombinant Antibody (clone IGELb4) (CAT#: FAMAB-0288YC)
IgE immune responses to a variety of environmental and synthetic agents are the hallmark of certain allergic diseases that affect 5-15% of the population. Provided herein is a antibody against trinitrophenyl (TNP).
Specific Inquiry
FuncS
Figure 1 Groups of three to five F1 mice were immunized with SRBC-TNP and HRBC preincubated with 0–50 μg of IgE anti-TNP (IGELb4) (solid circles) or IgG2b anti-TNP (1B4) (open circles). Five days later the direct SRBC-specific (solid line) and HRBC-specific (broken line) PFC/spleen were assayed.
Karlsson, M. C., Wernersson, S., de Ståhl, T. D., Gustavsson, S., & Heyman, B. (1999). Efficient IgG-mediated suppression of primary antibody responses in Fcγ receptor-deficient mice. Proceedings of the National Academy of Sciences, 96(5), 2244-2249.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgE
- Specificity
- TNP
- Clone
- IGELb4
- Applications
- FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. should be carefully titrated in specific assays.
Target
- Alternative Names
- TNP; 2,4,6-trinitrophenol; Picric acid
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Immunotoxin Products
IgG Antibody Products
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G064R | Anti-TNP immunotoxin (IgM)-RTA | Cytotoxicity assay, Function study |
Customer Reviews and Q&As
Customer Review
Q&As
Reliable and reproducible
I am very happy with the specificity of the Mouse Anti-TNP Recombinant Antibody (clone IGELb4). It increased the reliability and repeatability of our immunological assays. The isotype compatibility provided a substantial advantage for our experimental requirements.
No cross-reactivity
Clone IGELb4's specificity for TNP is second to none. We haven't encountered any cross-reactivity issues, making this antibody an essential tool in our lab. It's great for any research focused on TNP-conjugated substances.
Easy storage and handling
Storage and handling of the Mouse Anti-TNP Recombinant Antibody (clone IGELb4) were straightforward, as detailed in the manual. The antibody maintained its integrity over multiple experiments, showing consistent performance. Truly a reliable product.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# FAMAB-0288YC, RRID: AB_3111325)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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