DRB1*01:01/Human House dust mite Der p1 (LRQMRTVTPIRMQGG) MHC Tetramer (CAT#: MHC-YF871)

This product is a MHC tetramer of biotinylated peptide/MHC complex composed House dust mite Der p1-derived peptide of LRQMRTVTPIRMQGG sequence covering 96-110 and DRB1*01:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.

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Specifications

  • Allele
  • DRB1*01:01
  • Class
  • Class II
  • MHC Species
  • Human
  • Antigen
  • House dust mite Der p1
  • Peptide
  • LRQMRTVTPIRMQGG
  • Range
  • 96-110
  • Application
  • FCM

Target

  • Antigen Introduction
  • Thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues.
  • Alternative Names
  • derp1; Der-p1

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Enables High-Resolution Analysis
The tetramer's bright fluorescence and minimal off-target binding allow us to detect rare Der p1-specific T-cells even in low-abundance samples. This sensitivity is vital for studying early-stage allergic sensitization in preclinical models.

Trusted for Reproducibility
Over multiple projects, this tetramer has delivered great consistency. Its performance in flow cytometry ensures reliable data, which is crucial for collaborative studies and securing grant funding for allergy research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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