DRB1*01:01/Human House dust mite Der p1 (LRQMRTVTPIRMQGG) MHC Tetramer
CAT#: MHC-YF871
This product is a MHC tetramer of biotinylated peptide/MHC complex composed House dust mite Der p1-derived peptide of LRQMRTVTPIRMQGG sequence covering 96-110 and DRB1*01:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specifications
- Allele
- DRB1*01:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- House dust mite Der p1
- Peptide
- LRQMRTVTPIRMQGG
- Range
- 96-110
- Application
- FCM
Target
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Enables High-Resolution Analysis
The tetramer's bright fluorescence and minimal off-target binding allow us to detect rare Der p1-specific T-cells even in low-abundance samples. This sensitivity is vital for studying early-stage allergic sensitization in preclinical models.
Trusted for Reproducibility
Over multiple projects, this tetramer has delivered great consistency. Its performance in flow cytometry ensures reliable data, which is crucial for collaborative studies and securing grant funding for allergy research.
Q&As
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Can this product be used for flow cytometry?
A: Yes, the tetramer is conjugated to a fluorescent label (e.g., PE) for flow cytometry. It allows quantification and characterization of Der p1-specific CD4+ T-cells in complex samples, making it invaluable for profiling immune responses in allergy models or patient-derived cells.
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How stable is the tetramer under typical lab conditions?
A: The tetramer is stable for 6-12 months when stored at 4°C in the dark. Avoid freeze-thaw cycles to maintain structural integrity. Its stability ensures consistent performance in long-term studies, such as longitudinal immune monitoring in allergy models.
View the frequently asked questions answered by Creative Biolabs Support.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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