H-2Dd/HIV IIIB gp120 (RGPGRAFVTI) MHC Pentamer (CAT#: MHC-YF497)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed IIIB gp120-derived peptide of RGPGRAFVTI sequence covering 318-327 and H-2Dd molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.

Specific Inquiry
  • Size:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • H-2Dd
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • IIIB gp120
  • Antigen Species
  • HIV
  • Peptide
  • RGPGRAFVTI
  • Range
  • 318-327
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Envelope glycoprotein gp160: Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.
  • Alternative Names
  • Env polyprotein; env; Envelope glycoprotein gp160

Downloads

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Customer Reviews and Q&As

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  • Amazing specificity and sensitivity
    I was impressed with the specificity and sensitivity of this pentamer. It's been invaluable in my research on antigen-specific T cell responses to HIV, especially in post-vaccination studies.
  • Great tool for studying HIV vaccine
    Great tool for tracking T cell responses in our HIV vaccine studies. It has enhanced our understanding of T cell dynamics and vaccine-induced immunity.
  • Satisfying customer support
    I appreciate the customer support for this product. They provided excellent guidance on usage, which made a big difference in our experimental outcomes.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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