Human Anti-ABCD1 scFv-Fc Chimera (VS-0325-FY180) (CAT#: VS-0325-FY180)
This is a recombinant antibody derived from a rabbit monoclonal antibody and further engineered for improved stability and affinity. It is a single-chain variable fragment (scFv) fused to the Fc region of a human IgG antibody. The antibody is designed for use in diagnostic kits to detect aldosterone levels in patients with metabolism-related diseases.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human ABCD1
- Species Reactivity
- Human
- Applications
- Immunoassay
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Human Adrenoleukodystrophy protein; ALD protein, ABCD1
- Gene ID
- 215
- UniProt ID
- P33897
- Long Name
- Human Adrenoleukodystrophy protein
- Sequence Similarities
- Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
- Cellular Localization
- Endoplasmic reticulum; Lysosome; Membrane; Mitochondrion; Peroxisome
- Post Translation Modifications
- Tyrosine-phosphorylated.
Glycosylation at Asn214
Ubiquitination at Lys708
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 1 site
- Protein Refseq
- XP_047297872.1; XP_047297873.1
- Function
- Coupled to the ATP-dependent transporter activity has also a fatty acyl-CoA thioesterase activity (ACOT) and hydrolyzes VLCFA-CoA into VLCFA prior their ATP-dependent transport into peroxisomes, the ACOT activity is essential during this transport process.
Recommended Products
Isotype Control
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "ABCD1"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
VS3-FY2187 | Rabbit Anti-ABCD1 Recombinant Antibody (clone R64-2S-2) | WB, IF, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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