Human Anti-ABCD1 scFv-Fc Chimera (VS-0325-FY180) (CAT#: VS-0325-FY180)

This is a recombinant antibody derived from a rabbit monoclonal antibody and further engineered for improved stability and affinity. It is a single-chain variable fragment (scFv) fused to the Fc region of a human IgG antibody. The antibody is designed for use in diagnostic kits to detect aldosterone levels in patients with metabolism-related diseases.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
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  • Datasheet
  • MSDS
  • COA

Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Specificity
  • Human ABCD1
  • Species Reactivity
  • Human
  • Applications
  • Immunoassay

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • Human Adrenoleukodystrophy protein; ALD protein, ABCD1
  • Long Name
  • Human Adrenoleukodystrophy protein
  • Sequence Similarities
  • Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
  • Cellular Localization
  • Endoplasmic reticulum; Lysosome; Membrane; Mitochondrion; Peroxisome
  • Post Translation Modifications
  • Tyrosine-phosphorylated.
    Glycosylation at Asn214
    Ubiquitination at Lys708
    Modification sites at PhosphoSitePlus
    Glycosylation from GlyGen 1 site
  • Function
  • Coupled to the ATP-dependent transporter activity has also a fatty acyl-CoA thioesterase activity (ACOT) and hydrolyzes VLCFA-CoA into VLCFA prior their ATP-dependent transport into peroxisomes, the ACOT activity is essential during this transport process.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "ABCD1"

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IgG Antibody Products
CAT Product Name Application Type
VS3-FY2187 Rabbit Anti-ABCD1 Recombinant Antibody (clone R64-2S-2) WB, IF, FC Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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