Rabbit Anti-ABCD1 Recombinant Antibody (clone R64-2S-2) (CAT#: VS3-FY2187)

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse and Rat ABCD1

• Species Reactivity
• Human, Mouse, Rat

• Clone
• R64-2S-2

• Applications
• Western Blot, Immunofluorescence, Flow Cytometry

• Conjugate
• Unconjugated

• MW
• The calculated weight of the target protein is approximately 83kDa, while the observed molecular weight stands at 83kDa.

• Related Disease
• Adrenoleukodystrophy and Hypoadrenocorticism, Familial

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• PBS (pH 7.4), 150 mM NaCl, 50% glycerol

• Preservative
• 0.02% Sodium azide

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000
  Immunofluorescence: 1/50-1/200
  Flow Cytometry: 1/50

• Alternative Names
• ATP Binding Cassette Subfamily D Member 1; ATP-Binding Cassette, Sub-Family D (ALD), Member 1; Adrenoleukodystrophy Protein; ALDP; ALD; ATP-Binding Cassette Sub-Family D Member 1; ABC42; AMN

• Gene ID
• 215

• UniProt ID
• P33897

• Sequence Similarities
• Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.

• Cellular Localization
• Endoplasmic reticulum, Lysosome, Membrane, Mitochondrion, Peroxisome

• Post Translation Modifications
• Tyrosine-phosphorylated. (P33897-ABCD1_HUMAN)
  Glycosylation at Asn214 (NX_P33897 [NX_P33897-1])
  Ubiquitination at Lys708 (NX_P33897 [NX_P33897-1])
  Modification sites at PhosphoSitePlus (P33897)
  Glycosylation from GlyGen (P33897) 1 site

• Protein Refseq
• XP_047297872.1; XP_047297873.1; XP_054182655.1; XP_054182656.1; NP_000024.2

• Function
• Coupled to the ATP-dependent transporter activity has also a fatty acyl-CoA thioesterase activity (ACOT) and hydrolyzes VLCFA-CoA into VLCFA prior their ATP-dependent transport into peroxisomes, the ACOT activity is essential during this transport process.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-054CQ
• Goat Anti-Rabbit IgG Antibody, R-PE

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-055CQ
• Chicken Anti-Rabbit IgG (H&L) Antibody

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