Human Anti-abrin toxin scFv-Fc Chimera (VS-0325-FY145) (CAT#: VS-0325-FY145)

This product is a panel of single-chain variable fragment-Fc (scFv-Fc) antibodies designed to neutralize abrin toxin. These antibodies are derived from a rabbit immune library and target both the A and B subunits of abrin. The scFv portion, derived from rabbit antibodies, is fused to the human IgG1 Fc region. This format may offer potential benefits in terms of stability and effector functions.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Immunogen
  • The immunogen was purified native abrin holotoxin administered to a rabbit.
  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Specificity
  • A. precatorius abrin toxin
  • Species Reactivity
  • A. precatorius
  • Applications
  • Neutralization

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • Abrin; Abrus precatorius abrin toxin
  • Long Name
  • Abrus precatorius abrin toxin
  • Function
  • Abrus precatorius abrin toxin is a highly potent ribosome-inactivating protein found in the seeds of the rosary pea plant. It inhibits protein synthesis and is extremely toxic to eukaryotic cells.

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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