Recombinant Human Anti-gag Soluble TCR (KIH) (VS-0622-YF7120)
CAT#: VS-0622-YF7120
Human TCR recognizes gag peptide (SLFNTIAVL) in the context of HLA-A*02. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specifications
- Host Species
- Human
- Target
- gag
- Species Reactivity
- HIV1
- Epitope
- SLFNTIAVL
- MHC
- HLA-A*02
- Type
- Soluble TCR (KIH)
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
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Effective for HIV Research
The Recombinant Human Anti-gag Soluble TCR enabled precise study of the HIV gag peptide's interaction with T cells. Its specificity in the HLA-A*02 context was crucial for our understanding of immune responses in HIV-positive samples, making it an invaluable addition to our virology research toolkit.
Study-Enhanced Precision
The precision afforded by this soluble TCR in identifying HIV-1 gag-specific immune responses is impressive. Its role in bolstering our study of viral peptide recognition has provided clearer pathways for further research into innovative treatment strategies.
Q&As
-
What specific peptide does this TCR target?
A: This TCR specifically targets the gag peptide SLFNTIAVL, crucial for studying antigen-specific T cell responses in HIV research.
-
Is this product available with different conjugates for detection purposes?
A: Yes, the Recombinant Human Anti-gag Soluble TCR is available without conjugation and can be custom-conjugated with PE, APC, FITC, Biotin, HRP, and others, to fit specific assay requirements.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "GAG"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-098 | Recombinant Anti-HIV-1 gag VHH Single Domain Antibody (PNBL-098) | WB, ELISA, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0709 | PE-A*02:01/HIV GAG (FLGKIWPS) MHC Tetramer | FCM, IHC | |
| MHC-CN0710 | APC-A*02:01/HIV GAG (FLGKIWPS) MHC Tetramer | FCM, IHC | |
| MHC-CN0711 | FITC-A*02:01/HIV GAG (FLGKIWPS) MHC Tetramer | FCM, IHC | |
| MHC-CN0712 | A*02:01/HIV GAG (FLGKIWPS) MHC Tetramer | FCM, IHC | |
| MHC-CN0713 | PE-A*02:01/HIV GAG (RTLNAWVKV) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-FY519 | Mouse Anti-gag Recombinant Antibody (clone 2506W0414) | ELISA | Mouse IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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