Human Anti-β-glucan (clone 1E12) scFv-Fc Chimera (CAT#: VS-0125-FY110)

The anti-β-glucan scFv-Fc recombinant antibody, β-glucan, is a polysaccharide widely found in the cell walls of many pathogenic fungi. It represents a novel immunotherapeutic agent derived from plant sources, intended for the treatment of candidiasis and other fungal infections. The development of these antibodies could provide new treatment options for various patient groups, aiding in the control of common fungal infections.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Species Reactivity
  • C. albicans
  • Clone
  • 1E12
  • Applications
  • Inhibition
  • Related Disease
  • Fungal infection

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Stabilizer
  • No Stabilizers
  • Sterility
  • 0.2 μM filtered
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • The anti-β-glucan monoclonal antibody scFv-Fc recombinant antibody retains its binding properties to β-glucan and antifungal activity, demonstrating potential to inhibit the growth of Candida albicans and prevent its adhesion to human epithelial cells. Furthermore, it enhances the killing effect of human polymorphonuclear leukocytes on Candida albicans, providing significant antifungal protection in animal models.

Target

  • Alternative Names
  • β-glucan, Glucanase, Glucan-binding protein

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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