Human Anti-phosphorylated RNA polymerase II scFv-Fc Chimera (VS-0325-FY173) (CAT#: VS-0325-FY173)

An "anti-phosphorylated RNA polymerase II scFv-Fc" refers to a recombinant antibody engineered to specifically bind to the phosphorylated form of RNA polymerase II, where the "scFv" part is a single-chain variable fragment providing antigen-binding specificity, and the "Fc" portion is the constant region of an immunoglobulin that allows for effector functions like immune cell activation when bound to its target antigen (phosphorylated RNA polymerase II).

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Immunogen
  • Phospho-YSPTSPSYSPTSPS-BSA conjugates with different serine phosphorylation patterns.
  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Specificity
  • Human phosphorylated RNA polymerase II
  • Species Reactivity
  • Human
  • Applications
  • IB, Chromatin Immunoprecipitation

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • Human RNA Polymerase II (phosphorylated); Pol II, RNAP II, pPol II (phosphorylated forms often denoted with a "p" prefix)
  • Long Name
  • Human RNA Polymerase II (phosphorylated)
  • Function
  • Human phosphorylated RNA polymerase II is the active form of RNA polymerase II, responsible for transcribing protein-coding genes. Phosphorylation of its C-terminal domain is crucial for initiating and regulating gene expression.

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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