Human Anti-SFTSV Gn scFv-Fc Chimera (VS-0325-FY195)

CAT#: VS-0325-FY195

Ab10 is a human monoclonal antibody specifically targeting the Gn glycoprotein of the SFTSV. It is engineered as an scFv fused to a human IgG1 Fc domain, providing enhanced stability and potential for therapeutic applications. This antibody was isolated from a phage-displayed library constructed from a patient who recovered from SFTS, indicating its potential for neutralizing the virus.

Specifications

  • Immunogen
  • SFTSV Gn glycoprotein (specifically, the extracellular domain comprising all ten lectin-binding domains fused with a human IgG Fc domain).
  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Specificity
  • Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) Gn
  • Species Reactivity
  • Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV)
  • Applications
  • Western Blot, ELISA, Immunofluorescence, Neutralization

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • Severe Fever with Thrombocytopenia Syndrome Virus Glycoprotein N; SFTSV Gn
  • Long Name
  • Severe Fever with Thrombocytopenia Syndrome Virus Glycoprotein N
  • Function
  • SFTSV Gn refers to the glycoprotein N of Severe Fever with Thrombocytopenia Syndrome Virus, which is involved in viral entry and is a target for neutralizing antibodies. It is a key component in the virus's ability to infect host cells.
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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Isotype Control

Secondary Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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