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ACP3

This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway.
Protein class

Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins

Predicted location

Intracellular, Membrane, Secreted (different isoforms)

Single cell type specificity

Group enriched (Cytotrophoblasts, Syncytiotrophoblasts, Hofbauer cells)

Immune cell specificity

Immune cell enhanced (eosinophil)

Cell line specificity

Cell line enhanced (BJ hTERT+, OE19, RPMI-8226, U-698, U-87 MG)

Interaction

Homodimer; dimer formation is required for phosphatase activity.

Molecular function

Hydrolase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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