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AIF1
Anti-AIF1 Recombinant Antibody Products
- AbPlus™ Anti-AIF1 Magnetic Beads (VS-0724-YC978) (VS-0724-YC978)
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- Target: AIF1
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]
Predicted location
Intracellular
Single cell type specificity
Group enriched (Kupffer cells, Hofbauer cells, Macrophages, Langerhans cells, monocytes)
Immune cell specificity
Group enriched (non-classical monocyte, intermediate monocyte, classical monocyte, neutrophil, myeloid DC)
Cell line specificity
Group enriched (HEL, HMC-1, NB-4, THP-1, U-937)
Interaction
Homodimer (Potential). Monomer. Interacts with LCP1.
Molecular function
Actin-binding
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