


BAD

Anti-BAD Products
- Rabbit Anti-NHP BAD Recombinant Antibody (VS-1024-XY46) (VS-1024-XY46)
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- Species Reactivity: Human, Mouse, Non-human primate, Rat
- Type: Rabbit IgG
- Application: WB, IF
- Chicken Anti-BAD Polyclonal IgY (BRD-0064MZ)
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- Species Reactivity: Human, Rat
- Type: Chicken antibody
- Application: WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IP
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For Research Use Only. Not For Clinical Use.
Background
Cancer-related genes, RAS pathway related proteins
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Forms heterodimers with the anti-apoptotic proteins, Bcl-X(L), Bcl-2 and Bcl-W. Also binds protein S100A10 (By similarity). The Ser-75/Ser-99 phosphorylated form binds 14-3-3 proteins (By similarity). Interacts with AKT1 and PIM3. Interacts (via BH3 domain) with NOL3 (via CARD domain); preventing the association of BAD with BCL2 (By similarity). Interacts with HIF3A (via C-terminus domain); the interaction reduces the binding between BAD and BAX (By similarity). Interacts with GIMAP3/IAN4 and GIMAP5/IAN5 (PubMed:16509771).