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CD16
Anti-CD16 Recombinant Antibody Products
- Human Anti-CD16 Recombinant Antibody (clone DJ130c) (FAMAB-1632CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: IP, WB, FC, IHC
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- Human Anti-CD16 Recombinant Antibody (clone B88-9) (FAMAB-1633CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: IP, FC, IF
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- Rat Anti-CD16 Recombinant Antibody (clone YFC 120.5) (FAMAB-1737CQ)
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- Species Reactivity: Cat, Human
- Type: Rat IgG2b
- Application: FC
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- Human Anti-CD16 Antibody (clone DJ130c), mRNA (FAMAB-1632CQ-mRNA)
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- Species Reactivity: Human
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- Rat Anti-CD16 Antibody (clone YFC 120.5), mRNA (FAMAB-1737CQ-mRNA)
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- Species Reactivity: Cat, Human
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- Mouse Anti-CD16 Recombinant Antibody (clone 3G8) (VS11-QX24)
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- Derivation: Mouse
- Species Reactivity: Human, Chimpanzee, Baboon, Cynomolgus monkey, Rhesus monkey, Pigtailed Macaque, Capuchin monkey, Squirrel monkey, Sooty Mangabey, Cotton-topped Tamarin, Marmoset
- Type: Mouse IgG1, κ
- Application: FC, SPR, Depletion, IP, IHC, Block
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- Human Anti-CD16 (clone B88-9) scFv-Fc Chimera (VS-0325-FY61)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: IP, FC, IF
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For Research Use Only. Not For Clinical Use.
Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.