CD28 & melanoma-associated proteoglycan
Anti-CD28 & melanoma-associated proteoglycan Recombinant Antibody Products
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- Target: CD28
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.