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CD28 & melanoma-associated proteoglycan
Loading...Anti-CD28 & melanoma-associated proteoglycan Products
- AbPlus™ Anti-CD28 Magnetic Beads (VS-0424-XY52) (VS-0424-XY52)
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- Target: CD28
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
Background
CD28 (CD28 Molecule) is a Protein Coding gene. Diseases associated with CD28 include Mycosis Fungoides and Sezary's Disease. Among its related pathways are Th2 Differentiation Pathway and RET signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding and SH3/SH2 adaptor activity. An important paralog of this gene is CTLA4.
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
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