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    CDC25C

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    Anti-CDC25C Products

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    For Research Use Only. Not For Clinical Use.


    This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described.
    Protein class

    Cancer-related genes, Enzymes, Metabolic proteins

    Predicted location

    Intracellular

    Single cell type specificity

    Cell type enhanced (Spermatocytes, Late spermatids, Early spermatids, Spermatogonia)

    Immune cell specificity

    Not detected in immune cells

    Cell line specificity

    Low cell line specificity

    Interaction

    Interacts with MAPK14 and 14-3-3 proteins. When phosphorylated on Ser-129 and/or Thr-130, interacts with PLK1. (Microbial infection) Interacts with HIV-1 Vpr; this interaction inactivates CDC25C phosphatase activity.

    Molecular function

    Hydrolase, Protein phosphatase

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