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CDC42BPG

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For Research Use Only. Not For Clinical Use.


Background

CDC42BPG May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity).
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Gastric mucus-secreting cells, Squamous epithelial cells, Paneth cells, Distal enterocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (BEWO, HaCaT, MCF7, RT4, SK-BR-3, T-47d)

Interaction

Homodimer and homotetramer via the coiled coil regions. Interacts tightly with GTP-bound but not GDP-bound CDC42 (By similarity).

Molecular function

Kinase, Serine/threonine-protein kinase, Transferase

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