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For Research Use Only. Not For Clinical Use.
Enzymes, Metabolic proteins
Intracellular
Cell type enhanced (Gastric mucus-secreting cells, Squamous epithelial cells, Paneth cells, Distal enterocytes)
Not detected in immune cells
Cell line enhanced (BEWO, HaCaT, MCF7, RT4, SK-BR-3, T-47d)
Homodimer and homotetramer via the coiled coil regions. Interacts tightly with GTP-bound but not GDP-bound CDC42 (By similarity).
Kinase, Serine/threonine-protein kinase, Transferase