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CEACAM6

Engineered Antibody Antibody Magnetic Beads
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease.
CEACAM6
Protein class

Cancer-related genes, CD markers

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Alveolar cells type 1, Distal enterocytes, Paneth cells, Club cells, Urothelial cells)

Immune cell specificity

Immune cell enhanced (neutrophil)

Cell line specificity

Cell line enriched (OE19)

Interaction

Homodimer; homodimerizes via its Ig-like V-type domain. Heterodimer with CEACAM8; heterodimerizes via its Ig-like V-type domain.

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For Research Use Only. Not For Clinical Use.

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