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CFL1
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- Recombinant Anti-human CFL1 Antibody (MOB-196)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, Neut, FuncS
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- Recombinant Mouse Anti-CFL1 Antibody (VS-0923-FY42) (VS-0923-FY42)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, WB
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- Recombinant Anti-human CFL1 Antibody Fab Fragment (MOB-196-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: RIA, ELISA, FuncS
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- Recombinant Anti-human CFL1 Antibody scFv Fragment (MOB-196-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: IF, Neut, FuncS
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- Recombinant Anti-human CFL1 VHH Single Domain Antibody (NAB-385-VHH)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: FUNC, FA, IP, ChiP
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- Recombinant Human Anti-human CFL1 Antibody scFv Fragment (MHH-196-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, IP, FuncS
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- Recombinant Human Anti-human CFL1 Antibody Fab Fragment (MHH-196-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: RIA, WB, FuncS
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- Anti-Mouse CFL1 Immunohistochemistry Kit (VS-0525-XY1399)
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- Species Reactivity: Human, Mouse, Rat, Sheep
- Target: CFL1
- Application: IHC
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- Anti-Human CFL1 Immunohistochemistry Kit (VS-0525-XY1398)
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- Species Reactivity: Human
- Target: CFL1
- Application: IHC
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- Anti-Monkey CFL1 Immunohistochemistry Kit (VS-0525-XY1400)
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- Species Reactivity: Human, Mouse, Rat, Monkey
- Target: CFL1
- Application: IHC
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- Anti-CFL1 Immunohistochemistry Kit (VS-0325-XY433)
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- Species Reactivity: Human, Mouse, Rat
- Target: CFL1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]