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CLDN2
Anti-CLDN2 Recombinant Antibody Products
- Recombinant Mouse Anti-Human CLDN2 Antibody (MOB-1102MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG1
- Application: WB, IHC
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- Mouse Anti-CLDN2 Recombinant Antibody (clone PT0311) (VS3-CJ1058)
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- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, IHC-P
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- Mouse Anti-CLDN2 Recombinant Antibody (clone 8H11) (VS3-WK1617)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IHC
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For Research Use Only. Not For Clinical Use.
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Proximal tubular cells, Ductal cells, Exocrine glandular cells, Proximal enterocytes, Pancreatic endocrine cells, Hepatocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (OE19)
Interaction
Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN1, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3 (By similarity).
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