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CTAG2

Anti-CTAG2 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.
Protein class

Cancer-related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Spermatogonia)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (GAMG, K-562, OE19, RPMI-8226, SK-BR-3, U-266/84)

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