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CTGF

CTGF (Connective Tissue Growth Factor) is a Protein Coding gene. Diseases associated with CTGF include Systemic Scleroderma and Renal Fibrosis. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and PAK Pathway. Gene Ontology (GO) annotations related to this gene include growth factor activity and integrin binding. An important paralog of this gene is NOV.
CTGF
Protein class

Cancer-related genes, Metabolic proteins, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Fibroblasts, Smooth muscle cells, Adipocytes, Extravillous trophoblasts, Cardiomyocytes)

Immune cell specificity

Immune cell enriched (naive B-cell)

Cell line specificity

Cell line enhanced (EFO-21, HUVEC TERT2, TIME)

Interaction

Monomer (PubMed:1654338). Interacts with TSKU (PubMed:30232710).

Molecular function

Heparin-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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