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CTSB
Anti-CTSB Recombinant Antibody Products
- AbPlus™ Anti-CTSB Magnetic Beads (VS-0724-YC144) (VS-0724-YC144)
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- Target: CTSB
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
CTSB (Cathepsin B) is a Protein Coding gene. Diseases associated with CTSB include Keratolytic Winter Erythema and Occlusion Of Gallbladder. Among its related pathways are Bacterial infections in CF airways and Innate Immune System. Gene Ontology (GO) annotations related to this gene include peptidase activity and cysteine-type peptidase activity. An important paralog of this gene is TINAGL1.
Protein class
Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Hofbauer cells, Kupffer cells, Macrophages)
Immune cell specificity
Group enriched (classical monocyte, intermediate monocyte, plasmacytoid DC, basophil, non-classical monocyte, myeloid DC)
Cell line specificity
Cell line enhanced (BJ hTERT+, fHDF/TERT166)
Interaction
Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. Interacts with SRPX2. Directly interacts with SHKBP1 (PubMed:16733801).
Molecular function
Hydrolase, Protease, Thiol protease
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