Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
+ Filter
Loading...
Custom Services order now ship next day

DAPK2

Recombinant Antibody Products Formats

Anti-DAPK2 Recombinant Antibody Products

More Infomation

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Late spermatids, Oligodendrocytes, Alveolar cells type 1, Proximal enterocytes)

Immune cell specificity

Group enriched (eosinophil, basophil, neutrophil)

Cell line specificity

Cell line enhanced (ASC diff, HaCaT, HMC-1, MCF7)

Interaction

Homodimer in its autoinhibited state. Active as monomer (By similarity). Isoform 2 but not isoform 1 can interact with ATF4. Interacts with 14-3-3 proteins YWHAB, YWHAE, YWHAG, YWHAH, YWHAQ, YWHAZ and SFN; the interaction requires DAPK2 phosphorylation at Thr-369 and suppresses DAPK2 kinase activity and DAPK2-induced apoptosis (PubMed:26047703).

Molecular function

Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase

More Types Infomation
Related Diseases
Bladder Cancer Bladder Cancer
  • 0
  • 0
Cart
    Inquiry
    Go to compare

    Go to compare