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DHRS2

Anti-DHRS2 Products
- AbPlus™ Anti-DHRS2 Magnetic Beads (VS-0724-YC397) (VS-0724-YC397)
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- Target: DHRS2
- Target Species: Human
- Application: IP, Protein Purification
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- Species Reactivity: Human
- Application: ELISA, WB
- Anti-DHRS2 Immunohistochemistry Kit (VS-0325-XY657)
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- Species Reactivity: Human
- Target: DHRS2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members of this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. Alternative promoter use and alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Protein class
Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Urothelial cells, Syncytiotrophoblasts, Extravillous trophoblasts, Theca cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (Hep G2, RT4, SK-BR-3, U-2 OS)
Interaction
Directly interacts with MDM2; this interaction occurs in the nucleus and does not target DHRS2 to degradation.
Molecular function
Oxidoreductase
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