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DLX4

Anti-DLX4 Products
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- Species Reactivity: Human
- Application: WB
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: ICC, IF, IP, IHC-P, WB
- Anti-DLX4 Immunohistochemistry Kit (VS-0525-XY2019)
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- Species Reactivity: Human
- Target: DLX4
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
Protein class
Disease related genes, Human disease related genes, Metabolic proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Extravillous trophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BEWO, CACO-2, GAMG, HAP1, K-562)
Molecular function
Developmental protein, DNA-binding
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