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DPP4
Anti-DPP4 Recombinant Antibody Products
- Human Anti-DPP4 Recombinant Antibody (HPAB-0215-YC) (HPAB-0215-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, Inhib, FuncS
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- Human Anti-DPP4 Recombinant Antibody (HPAB-0216-YC) (HPAB-0216-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, Inhib
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- Mouse Anti-DPP4 Recombinant Antibody (HPAB-0213-YC) (HPAB-0213-YC)
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- Species Reactivity: Human, Porcine
- Type: Mouse IgG2b
- Application: FC, FuncS
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- Human Anti-DPP4 Recombinant Antibody (HPAB-0214-YC) (HPAB-0214-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, Inhib
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- Rabbit Anti-DPP4 Recombinant Antibody (clone JM11-42) (MRO-0290-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Human Anti-DPP4 Recombinant Antibody (HPAB-0217-YC) (HPAB-0217-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, Inhib
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- Human Anti-DPP4 Recombinant Antibody (HPAB-3029LY) (HPAB-3029LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC
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- Mouse Anti-DPP4 Recombinant Antibody (clone OX61) (FAMAB-1627CQ)
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- Species Reactivity: Rat
- Type: Mouse IgG2a
- Application: ICC, IP, RIA, WB, FC, IF, IHC
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- Mouse Anti-DPP4 Antibody (clone OX61), mRNA (FAMAB-1627CQ-mRNA)
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- Species Reactivity: Rat
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- Mouse Anti-DPP4 Antibody (clone MK-0431), mRNA (PABL-690-mRNA)
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- Species Reactivity: Rat
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- Mouse Anti-DPP4 Recombinant Antibody; Fab Fragment (HPAB-0213-YC-F(E)) (HPAB-0213-YC-F(E))
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- Species Reactivity: Human, Porcine
- Type: Mouse Fab
- Application: FC, FuncS
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- Human Anti-DPP4 Recombinant Antibody; Fab Fragment (HPAB-0214-YC-F(E)) (HPAB-0214-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-DPP4 Recombinant Antibody; Fab Fragment (HPAB-0215-YC-F(E)) (HPAB-0215-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-DPP4 Recombinant Antibody; Fab Fragment (HPAB-0216-YC-F(E)) (HPAB-0216-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-DPP4 Recombinant Antibody; Fab Fragment (HPAB-0217-YC-F(E)) (HPAB-0217-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-DPP4 Recombinant Antibody; scFv Fragment (HPAB-3029LY-S(P)) (HPAB-3029LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC
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- Human Anti-DPP4 Recombinant Antibody; Fab Fragment (HPAB-3029LY-F(E)) (HPAB-3029LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
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- Mouse Anti-DPP4 Recombinant Antibody; scFv Fragment (HPAB-0213-YC-S(P)) (HPAB-0213-YC-S(P))
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- Species Reactivity: Human, Porcine
- Type: Mouse scFv
- Application: FC, FuncS
Compare
- Human Anti-DPP4 Recombinant Antibody; scFv Fragment (HPAB-0214-YC-S(P)) (HPAB-0214-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
Compare
- Human Anti-DPP4 Recombinant Antibody; scFv Fragment (HPAB-0215-YC-S(P)) (HPAB-0215-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
Compare
- Human Anti-DPP4 Recombinant Antibody; scFv Fragment (HPAB-0216-YC-S(P)) (HPAB-0216-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
Compare
- Human Anti-DPP4 Recombinant Antibody; scFv Fragment (HPAB-0217-YC-S(P)) (HPAB-0217-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- CytoStream™ Mouse Anti-DPP4 Recombinant Antibody (VS-0225-XY100) (VS-0225-XY100)
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- Species Reactivity: Rat
- Type: Mouse IgG2a, kappa
- Application: FC
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For Research Use Only. Not For Clinical Use.
DPP4 is a gene encoding a cell surface protease involved in the regulation of various physiological processes, including glucose metabolism and immune regulation. DPP4 cleaves peptides such as incretins, which are hormones that enhance insulin secretion in response to meals. In addition to its role in diabetes and metabolic disorders, DPP4 is involved in immune cell function, influencing T cell activation and the inflammatory response. It is also a receptor for the Middle East respiratory syndrome coronavirus (MERS-CoV), making it relevant in infectious disease research.
Protein class
CD markers, Enzymes, FDA approved drug targets, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Syncytiotrophoblasts, Cytotrophoblasts, Proximal tubular cells)
Immune cell specificity
Immune cell enhanced (MAIT T-cell)
Cell line specificity
Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+, RPTEC TERT1)
Interaction
Monomer. Homodimer (PubMed:12832764, PubMed:15448155, PubMed:17287217, PubMed:12646248, PubMed:12483204, PubMed:12906826). Heterodimer with Seprase (FAP) (PubMed:16651416). Requires homodimerization for optimal dipeptidyl peptidase activity and T-cell costimulation. Found in a membrane raft complex, at least composed of BCL10, CARD11, DPP4 and IKBKB (PubMed:17287217). Associates with collagen (PubMed:8526932). Interacts with PTPRC; the interaction is enhanced in an interleukin-12-dependent manner in activated lymphocytes (PubMed:12676959). Interacts (via extracellular domain) with ADA; does not inhibit its dipeptidyl peptidase activity (PubMed:15016824, PubMed:10951221, PubMed:14691230, PubMed:7907293, PubMed:8101391). Interacts with CAV1 (via the N-terminus); the interaction is direct (PubMed:17287217). Interacts (via cytoplasmic tail) with CARD11 (via PDZ domain); its homodimerization is necessary for interaction with CARD11 (PubMed:17287217). Interacts with IGF2R; the interaction is direct (PubMed:10900005). Interacts with GPC3 (PubMed:17549790). Interacts with human coronavirus-EMC spike protein and acts as a receptor for this virus (PubMed:23486063). (Microbial infection) Interacts with MERS coronavirus/MERS-CoV spike protein.
Molecular function
Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease
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