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Ebi3

Anti-Ebi3 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Ebi3
Predicted location

Secreted

Single cell type specificity

Group enriched (monocytes, Extravillous trophoblasts, Syncytiotrophoblasts)

Immune cell specificity

Group enriched (memory B-cell, naive B-cell, non-classical monocyte, intermediate monocyte)

Cell line specificity

Cell line enriched (HDLM-2)

Interaction

Heterodimer with IL27/IL27A; not disulfide-linked (PubMed:12121660). This heterodimer is known as interleukin IL-27 (PubMed:12121660). Heterodimer with IL12A; not disulfide-linked (PubMed:9342359). This heterodimer is known as interleukin IL-35 (PubMed:9342359). Interacts with SQSTM1 (PubMed:8551575).

Molecular function

Cytokine

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