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Ebi3
Anti-Ebi3 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Predicted location
Secreted
Single cell type specificity
Group enriched (monocytes, Extravillous trophoblasts, Syncytiotrophoblasts)
Immune cell specificity
Group enriched (memory B-cell, naive B-cell, non-classical monocyte, intermediate monocyte)
Cell line specificity
Cell line enriched (HDLM-2)
Interaction
Heterodimer with IL27/IL27A; not disulfide-linked (PubMed:12121660). This heterodimer is known as interleukin IL-27 (PubMed:12121660). Heterodimer with IL12A; not disulfide-linked (PubMed:9342359). This heterodimer is known as interleukin IL-35 (PubMed:9342359). Interacts with SQSTM1 (PubMed:8551575).
Molecular function
Cytokine
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