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For Research Use Only. Not For Clinical Use.
Creative Biolabs is a leading company specializing in the delivery of innovative anti-GABA-A synaptic receptor recombinant antibody products. Our state-of-the-art facilities and experienced scientists enable us to deliver high-quality, custom-designed antibodies tailored to specific research and therapeutic needs. Whether you're investigating the intricate mechanisms of neurological disorders or developing novel therapeutics, our anti-GABA-A synaptic receptor recombinant antibody has the potential to serve as a useful tool to advance your research.
GABA-A synaptic receptors, the most prevalent GABA-A synaptic receptors in the mammalian brain, are pentagonal, heterogeneous polypeptide oligomers embedded in nerve cell membranes. These receptors, composed of five subunits, possess multiple binding sites, including those for GABA, benzodiazepines, and chloride ions. Recognized as a crucial target for neurological disorders like anxiety and epilepsy, GABA-A synaptic receptors offer a promising avenue for therapeutic intervention. Further research is essential to uncover their potential in addressing a wider range of complex neurological diseases.
γ-aminobutyric acid type A receptor; GABAA receptor; GABA-A receptor; GABAA synaptic receptor; GABA-A synaptic receptor.
Creative Biolabs provides a broad spectrum of high-quality anti-GABA-A receptor recombinant antibodies in a variety of forms to meet a wide range of research requirements. Our antibodies have been thoroughly verified for optimal performance in a variety of applications, ensuring outstanding specificity, sensitivity, and reproducibility when investigating the complicated functions of GABA-A receptors in neurological processes and illnesses.
Table 1. Featured anti-GABA-A synaptic receptor recombinant antibody products at Creative Biolabs.
Cat. No. | Product Name | Target Species | Host Species | Applications |
VS-0824-YJ42 | Human Anti-GABA-A synaptic receptor Recombinant Antibody (Clone CMG201) | Human | Human IgG1 kappa | Inhib |
VS-0824-YJ42 | Human Anti-GABA-A synaptic receptor Recombinant Antibody (Clone CMG202) | Human | Human IgG1 lambda | Antagonist |
Creative Biolabs adheres to stringent quality control standards throughout the entire antibody production process. Our dedicated team of scientists leverages advanced techniques to ensure the highest quality and performance of our anti-GABA-A receptor antibodies. In addition, to ensure product consistency and dependability, rigorous testing and validation are carried out, such as sequence verification, expression optimization, purification, and functional characterization. By emphasizing quality and precision, we enable researchers to make significant discoveries in their fields.
Creative Biolabs leverages advanced genetic engineering to develop high-quality, custom antibodies targeting the GABA-A receptor, ensuring a reliable and consistent supply for diverse research applications.
Featured Anti-GABA-A synaptic receptor Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-GABA-A synaptic receptor recombinant antibody production.
Fig.2 Gram-scale anti-GABA-A synaptic receptor recombinant antibody production.
Creative Biolabs provides an extensive choice of high-quality recombinant antibodies targeting the GABA-A synaptic receptor, developed to address a wide range of research requirements and experimental applications.
Fig.3 Full-length anti-GABA-A synaptic receptor recombinant antibody production and modalities.
Table 2. Public drug targeting GABA-A synaptic receptor.
Company | Research Phase | Classification | Condition |
Hedonist Biochemical Technologies (Originator) | Launched |
Bismuth Complexes Fixed-Dose Combinations Natural Products |
Lesion, skin |
Bausch Health (Originator) Valeant (Bausch Health) |
Launched | Fixed-Dose Combinations | Irritable bowel syndrome |
AcelRx (Originator) | Discontinued | Fixed-Dose Combinations |
Anxiety disorders Pain |
King's College London University of Newcastle upon Tyne |
Clinical |
Chemosensitizers Herbals |
Dementia, Alzheimer type |
Lupin (Originator) | Biological Testing |
Herbals Saponins |
Epilepsy |
Bayer (Originator) | Biological Testing |
Depsipeptides Macrocyclic Peptides Natural Products |
Cancer Infection, bacterial Infection, fungal Infection, helminthic |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
Table 3. Clinical drug targeting GABA-A synaptic receptor.
Company | Research Phase | Classification | Condition |
Simcere Pharmaceutical (Originator) Yantai Yenepharma |
Launched - 2020 |
Fixed-Dose Combinations Natural Products |
Amyotrophic lateral sclerosis Stroke Stroke, ischemic |
Cadila Pharmaceuticals (Originator) | Launched - 2009 |
Alkaloids Fixed-Dose Combinations Natural Products Prodrugs Rifamycins |
Tuberculosis |
Allergan Aralez Pharmaceuticals Novartis Tribute Pharmaceuticals (Aralez Pharmaceuticals) |
Launched |
Barbiturates, Sedative/Hypnotics Cancer Immunotherapy Fixed-Dose Combinations Morphinans Natural Products Prodrugs |
Tension-type headache |
Allergan | Launched |
Barbiturates, Sedative/Hypnotics Cancer Immunotherapy Fixed-Dose Combinations Morphinans Natural Products Prodrugs |
Tension-type headache |
Sequential Medicine (Originator) | Phase III |
Benzodiazepines, Anxiolytics Fixed-Dose Combinations Prodrugs |
Insomnia |
Melt Pharmaceuticals (Originator) | Phase III |
Benzodiazepines, Anxiolytics Fixed-Dose Combinations |
Pain Sedation |
Embera NeuroTherapeutics Louisiana State University (Originator) |
Phase II/III | Fixed-Dose Combinations |
Cocaine dependence Smoking cessation therapy |
Incannex (Originator) | Preclinical |
Cannabinoids Multi-Component Products Natural Products Prodrugs Taxanes |
Brain concussion |
Tageza Biopharmaceuticals (Originator) Tel Hashomer Medical Res Infrastr & Serv (Originator) |
Biological Testing |
Cancer Immunotherapy Murine Monoclonal Antibodies |
Cancer |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
To delve deeper into the specific details of Creative Biolabs' anti-GABAAR recombinant antibody products and their potential applications in your research, please do not hesitate to get in touch with us.