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Anti-GABRG2 Recombinant Antibody Products

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Anti-GABRG2 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs is a leading company specializing in the delivery of innovative anti-GABA-A synaptic receptor recombinant antibody products. Our state-of-the-art facilities and experienced scientists enable us to deliver high-quality, custom-designed antibodies tailored to specific research and therapeutic needs. Whether you're investigating the intricate mechanisms of neurological disorders or developing novel therapeutics, our anti-GABA-A synaptic receptor recombinant antibody has the potential to serve as a useful tool to advance your research.

GABA-A Synaptic Receptor: A Versatile Target for Neurological Diseases

GABA-A synaptic receptors, the most prevalent GABA-A synaptic receptors in the mammalian brain, are pentagonal, heterogeneous polypeptide oligomers embedded in nerve cell membranes. These receptors, composed of five subunits, possess multiple binding sites, including those for GABA, benzodiazepines, and chloride ions. Recognized as a crucial target for neurological disorders like anxiety and epilepsy, GABA-A synaptic receptors offer a promising avenue for therapeutic intervention. Further research is essential to uncover their potential in addressing a wider range of complex neurological diseases.

Alternative Names

γ-aminobutyric acid type A receptor; GABAA receptor; GABA-A receptor; GABAA synaptic receptor; GABA-A synaptic receptor.

Background

GABAA receptors are part of the greater Cys-loop receptor family of pentameric ligand-gated ion channels. The GABAA receptors form anion-selective channels, and generally act to dampen neuronal excitability. They are usually heteromeric, assembling from a panel of 19 subunits. The most common isoform at synapses comprises two α1 subunits, two β subunits, and one γ2 subunit.

Anti-GABA-A Synaptic Receptor Recombinant Antibody Products

Creative Biolabs provides a broad spectrum of high-quality anti-GABA-A receptor recombinant antibodies in a variety of forms to meet a wide range of research requirements. Our antibodies have been thoroughly verified for optimal performance in a variety of applications, ensuring outstanding specificity, sensitivity, and reproducibility when investigating the complicated functions of GABA-A receptors in neurological processes and illnesses.

Table 1. Featured anti-GABA-A synaptic receptor recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
VS-0824-YJ42 Human Anti-GABA-A synaptic receptor Recombinant Antibody (Clone CMG201) Human Human IgG1 kappa Inhib
VS-0824-YJ42 Human Anti-GABA-A synaptic receptor Recombinant Antibody (Clone CMG202) Human Human IgG1 lambda Antagonist

Creative Quality Control

Creative Biolabs adheres to stringent quality control standards throughout the entire antibody production process. Our dedicated team of scientists leverages advanced techniques to ensure the highest quality and performance of our anti-GABA-A receptor antibodies. In addition, to ensure product consistency and dependability, rigorous testing and validation are carried out, such as sequence verification, expression optimization, purification, and functional characterization. By emphasizing quality and precision, we enable researchers to make significant discoveries in their fields.

Customer Reviews

Excellent
Sh***a
Human Anti-GABA-A synaptic receptor Recombinant Antibody (VS-0824-YJ42) (VS-0824-YJ42)
For my research, I utilized Creative Biolabs' anti-GABA-A synaptic receptor recombinant antibody. This antibody proved to be exceptionally specific, enabling precise targeting of the GABA-A receptor and minimizing non-specific binding. This high degree of specificity significantly enhanced the accuracy and reliability of my experimental results.
18/Apr/2021
Excellent
Sp***a
Human Anti-GABA-A synaptic receptor Recombinant Antibody (VS-0824-YJ42) (VS-0824-YJ42)
I was blown away by the performance of Creative Biolabs' anti-GABAAR recombinant antibody. It's like they've cracked the code for GABA-A research! The specificity is incredible - it's like a laser beam, zeroing in on the target without any off-target effects. This precision has significantly improved the quality of my Western blots and immunohistochemistry experiments. I'm so grateful for this powerful tool that's accelerated my research and brought me closer to unraveling the mysteries of GABAergic neurotransmission.
27/Aug/2023

Anti-GABA-A synaptic receptor Recombinant Antibody Production

Creative Biolabs leverages advanced genetic engineering to develop high-quality, custom antibodies targeting the GABA-A receptor, ensuring a reliable and consistent supply for diverse research applications.

Featured Anti-GABA-A synaptic receptor Recombinant Antibody Production Platforms Fig.1 Milligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-GABA-A synaptic receptor recombinant antibody production.

Fig.2 Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-GABA-A synaptic receptor recombinant antibody production.

Anti-GABA-A Synaptic Receptor Recombinant Antibody Modalities

Creative Biolabs provides an extensive choice of high-quality recombinant antibodies targeting the GABA-A synaptic receptor, developed to address a wide range of research requirements and experimental applications.

Fig.3 GABA-A synaptic receptor antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-GABA-A synaptic receptor recombinant antibody production and modalities.

GABAAR-Targeted Drug Information

Public Drug Information Targeting GABA-A synaptic receptor

Table 2. Public drug targeting GABA-A synaptic receptor.

Company Research Phase Classification Condition
Hedonist Biochemical Technologies (Originator) Launched Bismuth Complexes
Fixed-Dose Combinations
Natural Products
Lesion, skin
Bausch Health (Originator)
Valeant (Bausch Health)
Launched Fixed-Dose Combinations Irritable bowel syndrome
AcelRx (Originator) Discontinued Fixed-Dose Combinations Anxiety disorders
Pain
King's College London
University of Newcastle upon Tyne
Clinical Chemosensitizers
Herbals
Dementia, Alzheimer type
Lupin (Originator) Biological Testing Herbals
Saponins
Epilepsy
Bayer (Originator) Biological Testing Depsipeptides
Macrocyclic Peptides
Natural Products
Cancer
Infection, bacterial
Infection, fungal
Infection, helminthic

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Clinical Drug Information Targeting GABA-A synaptic receptor

Table 3. Clinical drug targeting GABA-A synaptic receptor.

Company Research Phase Classification Condition
Simcere Pharmaceutical (Originator)
Yantai Yenepharma
Launched - 2020 Fixed-Dose Combinations
Natural Products
Amyotrophic lateral sclerosis
Stroke
Stroke, ischemic
Cadila Pharmaceuticals (Originator) Launched - 2009 Alkaloids
Fixed-Dose Combinations
Natural Products
Prodrugs
Rifamycins
Tuberculosis
Allergan
Aralez Pharmaceuticals
Novartis
Tribute Pharmaceuticals (Aralez Pharmaceuticals)
Launched Barbiturates, Sedative/Hypnotics
Cancer Immunotherapy
Fixed-Dose Combinations
Morphinans
Natural Products
Prodrugs
Tension-type headache
Allergan Launched Barbiturates, Sedative/Hypnotics
Cancer Immunotherapy
Fixed-Dose Combinations
Morphinans
Natural Products
Prodrugs
Tension-type headache
Sequential Medicine (Originator) Phase III Benzodiazepines, Anxiolytics
Fixed-Dose Combinations
Prodrugs
Insomnia
Melt Pharmaceuticals (Originator) Phase III Benzodiazepines, Anxiolytics
Fixed-Dose Combinations
Pain
Sedation
Embera NeuroTherapeutics
Louisiana State University (Originator)
Phase II/III Fixed-Dose Combinations Cocaine dependence
Smoking cessation therapy
Incannex (Originator) Preclinical Cannabinoids
Multi-Component Products
Natural Products
Prodrugs
Taxanes
Brain concussion
Tageza Biopharmaceuticals (Originator)
Tel Hashomer Medical Res Infrastr & Serv (Originator)
Biological Testing Cancer Immunotherapy
Murine Monoclonal Antibodies
Cancer

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

To delve deeper into the specific details of Creative Biolabs' anti-GABAAR recombinant antibody products and their potential applications in your research, please do not hesitate to get in touch with us.

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