IAPP

Tetramer Products Soluble T Cell Receptor Products Recombinant Antibody Products Functional Antibody Products Formats

Anti-IAPP Recombinant Antibody Products

Mouse Anti-IAPP Recombinant Soluble TCR (BDC-5.2.9) (scTCR-267ZP-S(P))
- Species Reactivity: Mouse
- Epitope: KCNTATCATQRLANFLVRSS
- MHC: HLA class II
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Recombinant Mouse Anti-IAPP Soluble TCR (BDC-5.2.9) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1022)
- Species Reactivity: Mouse
- Epitope: KCNTATCATQRLANFLVRSS
- MHC: HLA class II
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Recombinant Mouse Anti-IAPP Soluble TCR (BDC-5.2.9) (C-Cys) (VS-0622-YF3730)
- Species Reactivity: Mouse
- Epitope: KCNTATCATQRLANFLVRSS
- MHC: HLA class II
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Recombinant Mouse Anti-IAPP Soluble TCR (BDC-5.2.9) (KIH) (VS-0622-YF6438)
- Species Reactivity: Mouse
- Epitope: KCNTATCATQRLANFLVRSS
- MHC: HLA class II
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For Research Use Only. Not For Clinical Use.

The antibodies specific for IAPP are used for the treatment and diagnosis of diseases from the group of Diabetes mellitus diseases, comprising type 1 diabetes (T1D), gestational diabetes, pre-diabetes, latent autoimmune diabetes of adults (LAD A; type 1, 5 diabetes) and/or type 2 diabetes (T2D).

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Group enriched (Early spermatids, Pancreatic endocrine cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (U-2 OS)

Interaction

Interacts with IDE and INS. Can form homodimers. Interaction with INS inhibits homodimerization and fibril formation.

Molecular function

Hormone

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