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ICAM3
Anti-ICAM3 Recombinant Antibody Products
- AbPlus™ Anti-ICAM3 Magnetic Beads (BH10) (VS-0424-XY142)
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- Target: ICAM3
- Target Species: Human
- Application: IP, Protein Purification
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- AbPlus™ Anti-ICAM3 Magnetic Beads (VS-0724-YC892) (VS-0724-YC892)
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- Target: ICAM3
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
Protein class
CD markers, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (NK-cells, T-cells, Hepatocytes, dendritic cells, B-cells, Plasma cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (Karpas-707, NB-4, RPMI-8226, U-266/84, U-937)
Interaction
Interacts with moesin/MSN.
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