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For Research Use Only. Not For Clinical Use.
Enzymes
Intracellular, Membrane (different isoforms)
Cell type enhanced (Excitatory neurons, Glandular and luminal cells, Langerhans cells, Basal keratinocytes, Suprabasal keratinocytes)
Not detected in immune cells
Cell line enhanced (A-431, ASC TERT1, HaCaT, HSkMC, hTCEpi)
Interacts with IL1RAP; the association is enhanced by IL36B indicative for an functional signaling complex and inhibited by IL36RN (By similarity).
Hydrolase, Receptor