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IL23R
Antibody-like Scaffold Protein Products
Antibody Magnetic Beads
AbPlus
Recombinant Antibody Products
Functional Antibody Products
Formats
Anti-IL23R Recombinant Antibody Products
- AbPlus™ Anti-IL23R Magnetic Beads (TC48-8B10.D5) (VS-0424-XY149)
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- Target: IL23R
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Early spermatids, Late spermatids, T-cells, Enteroendocrine cells)
Immune cell specificity
Immune cell enriched (MAIT T-cell)
Cell line specificity
Cell line enhanced (HL-60, HMC-1, K-562, U-2197)
Interaction
Heterodimer with IL12RB1. In presence of IL23, the heterodimer forms the IL23 receptor. Interacts with JAK2 and in presence of IL23 with STAT3.
Molecular function
Receptor
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