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For Research Use Only. Not For Clinical Use.


Background

The protein encoded by this gene is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system. During development of the limbic system, this encoded protein is found on the surface of axonal membranes and growth cones, where it acts as a selective homophilic adhesion molecule, and guides the development of specific patterns of neuronal connections.
Protein class

Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Astrocytes, Oligodendrocyte precursor cells, Inhibitory neurons, Excitatory neurons, Oligodendrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, SH-SY5Y, WM-115)

More Types Infomation
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