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MAP3K10

Anti-MAP3K10 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Horizontal cells, Excitatory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Low cell line specificity

Interaction

Homodimer. Interacts with SH3RF2.

Molecular function

Kinase, Serine/threonine-protein kinase, Transferase

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