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MAP3K14
Anti-MAP3K14 Recombinant Antibody Products
- Human Anti-MAP3K14 Antibody, mRNA (TAB-512CL-mRNA)
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- Species Reactivity: Human
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For Research Use Only. Not For Clinical Use.
This is an antibody capable of specifically binding the amino acid sequence of NF-&kgr B-inducing kinase (NIK) MAP3K14, used for treatment including malignant diseases and diseases associated with pathological immune responses, such as autoimmune, allergic, inflammatory, and transplantation-related diseases.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (monocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (A549, U-251 MG)
Interaction
Interacts with TRAF2, TRAF5, TRAF6, IKKA and NFKB2/P100 (By similarity). Interacts with TRAF3 and PELI3. Interacts with NIBP; the interaction is direct. Interacts with ARRB1 and ARRB2. Interacts with GRB10. Interacts with ZFP91. Interacts with NLRP12; this interaction promotes proteasomal degradation of MAP3K14. Directly interacts with DDX3X (PubMed:30341167). Interacts (via C-terminus and kinase domain) with PPPC3A (via N-terminus) and PPP3CB (By similarity).
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
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