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MAPK4
Anti-MAPK4 Recombinant Antibody Products
- Anti-MAPK4 Immunohistochemistry Kit (VS-0325-XY1300)
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- Species Reactivity: Human, Mouse, Rat
- Target: MAPK4
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets. Alternative splicing results in multiple transcript variants.
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Astrocytes, Excitatory neurons, Late spermatids, Muller glia cells, Inhibitory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HAP1, HeLa, NTERA-2, SCLC-21H, SH-SY5Y, SK-MEL-30)
Interaction
Homodimer. Heterodimer with ERK3/MAPK6. Interacts with (via FRIEDE motif) MAPKAPK5 (By similarity).
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
More Types Infomation
Related Signaling Pathways
FcεR1 Signaling Pathway
TCR Signaling Pathway
Related Diseases
Maturity Onset Diabetes of the Young