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MAPK4

Anti-MAPK4 Products

Hi-Affi™ Recombinant Rabbit Anti-MAPK4 Monoclonal Antibody (DS2156AB) (MOR-2156)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, FC
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Anti-MAPK4 Immunohistochemistry Kit (VS-0325-XY1300)
- Species Reactivity: Human, Mouse, Rat
- Target: MAPK4
- Application: IHC
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Anti-Mouse MAPK4 Immunohistochemistry Kit (VS-0525-XY4240)
- Species Reactivity: Human, Mouse, Rat
- Target: MAPK4
- Application: IHC
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Anti-Human MAPK4 Immunohistochemistry Kit (VS-0525-XY4239)
- Species Reactivity: Human
- Target: MAPK4
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Background

Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets. Alternative splicing results in multiple transcript variants.

Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Astrocytes, Excitatory neurons, Late spermatids, Muller glia cells, Inhibitory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HAP1, HeLa, NTERA-2, SCLC-21H, SH-SY5Y, SK-MEL-30)

Interaction

Homodimer. Heterodimer with ERK3/MAPK6. Interacts with (via FRIEDE motif) MAPKAPK5 (By similarity).