+ Filter
Loading...
NFAM1
Loading...Anti-NFAM1 Products
CompareCan't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a type I membrane receptor that activates cytokine gene promoters such as the IL-13 and TNF-alpha promoters. The encoded protein contains an immunoreceptor tyrosine-based activation motif (ITAM) and is thought to regulate the signaling and development of B-cells.
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Kupffer cells, monocytes, Macrophages, Hofbauer cells, granulocytes)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enriched (THP-1)
Interaction
No direct interaction with the B-cell antigen receptor (BCR). Interacts with SYK; probably involved in BCR signaling. Interacts with ZAP70 (By similarity).
More Types Infomation