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For Research Use Only. Not For Clinical Use.
Plasma proteins, Transporters
Secreted
Cell type enhanced (Adipocytes, Fibroblasts, Smooth muscle cells, Endothelial cells)
Group enriched (eosinophil, neutrophil)
Cell line enhanced (BJ hTERT+, hTERT-RPE1, U-2197)
Interacts with FBLN1. Interacts (via CTCK domain) with NOTCH1 (via the EGF-like repeat region) (PubMed:12050162). Interacts with GJA1/CX43 (PubMed:15181016, PubMed:15213231). Interacts with ITGA5:ITGB1, ITGAV:ITGB3 and ITGAV:ITGB5 (PubMed:12695522, PubMed:15611078). Interacts with ZDHHC22; the interaction may lead to CCN3 palmitoylation (By similarity).
Growth factor