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Natalizumab

Anti-Natalizumab Products

Human Anti-Natalizumab Recombinant Antibody (clone NAA84) (PABJ-0118)
- Species Reactivity: Human
- Type: Human IgG1, λ
- Application: ELISA, Neut
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Human Anti-Natalizumab Recombinant Antibody (clone NAA32) (PABJ-0119)
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
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Human Anti-Natalizumab Antibody (clone NAA84), mRNA (PABJ-0118-mRNA)
- Species Reactivity: Human
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Human Anti-Natalizumab Antibody (clone NAA32), mRNA (PABJ-0119-mRNA)
- Species Reactivity: Human
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Human Anti-Natalizumab Recombinant Antibody (clone NAA84); scFv Fragment (PABJ-0118-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Neut
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Human Anti-Natalizumab Recombinant Antibody (clone NAA32); scFv Fragment (PABJ-0119-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Human Anti-Natalizumab Recombinant Antibody (clone NAA84); Fab fragment (PABJ-0118-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Neut
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Human Anti-Natalizumab Recombinant Antibody (clone NAA32); Fab fragment (PABJ-0119-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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For Research Use Only. Not For Clinical Use.

Background

Natalizumab, a humanized monoclonal IgG4 antibody to α4 integrins, is used to treat patients with relapsing-remitting multiple sclerosis (MS), but in about 6% of the cases persistent neutralizing anti-drug antibodies (ADAs) are induced leading to therapy discontinuation.