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Nectin2
Anti-Nectin2 Recombinant Antibody Products
- AbPlus™ Anti-NECTIN2 Magnetic Beads (VS-0724-YC1270) (VS-0724-YC1270)
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- Target: NECTIN2
- Target Species: Human
- Application: IP, Protein Purification
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- AbPlus™ Anti-Nectin2 Magnetic Beads (VS-0724-YC1308) (VS-0724-YC1308)
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- Target: Nectin2
- Target Species: Mouse
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
Predicted to enable ATP binding activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple sclerosis. Orthologous to human PVR (PVR cell adhesion molecule) and NECTIN2 (nectin cell adhesion molecule 2).
Protein class
CD markers, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Pancreatic endocrine cells, Ductal cells, Exocrine glandular cells, Adipocytes, Glandular and luminal cells)
Immune cell specificity
Immune cell enhanced (eosinophil)
Cell line specificity
Low cell line specificity
Interaction
Can form trans-heterodimers with NECTIN3 (By similarity). Interacts with CD226 or with PVRIG; these interactions are competitive and have a differential functional outcome on T-cell activation, either positive or negative, respectively. Binds with low affinity to TIGIT. (Microbial infection) Interacts with herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV) envelope glycoprotein D (PubMed:11602758, PubMed:9657005).
Molecular function
Host cell receptor for virus entry, Receptor
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