PAN2

Formats

Anti-PAN2 Recombinant Antibody Products

Recombinant Mouse anti-Human PAN2 Monoclonal antibody (EML1225) (MOB-1529CT)
- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.

This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3 to 5 exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex (PubMed:14583602, PubMed:23932717). Interacts with ZFP36 (By similarity).

Molecular function

Exonuclease, Hydrolase, Nuclease

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