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PRPH
Anti-PRPH Recombinant Antibody Products
- AbPlus™ Anti-Prph Magnetic Beads (VS-0724-YC326) (VS-0724-YC326)
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- Target: Prph
- Target Species: Mouse, Rat
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
Predicted to enable structural molecule activity. Acts upstream of or within intermediate filament cytoskeleton organization. Located in C-fiber; intermediate filament; and photoreceptor outer segment membrane. Is expressed in several structures, including alimentary system; nervous system; and olfactory system. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 1. Orthologous to human PRPH (peripherin).
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Group enriched (Late spermatids, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (AN3-CA)
Interaction
Forms homodimers (in vitro) (By similarity). Homopolymerizes into a filamentous network (in vitro) (PubMed:15446584). Forms heterodimers with NEFL, NEFM or NEFH (in vitro) (By similarity). Interacts with DST (via C-terminus) (By similarity). Interacts with RAB7A; the interaction is direct (PubMed:23179371). Interacts with PRKCE (via phorbol-ester/DAG-type 2 domain) (PubMed:18408015).
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