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For Research Use Only. Not For Clinical Use.
Disease related genes, Human disease related genes
Membrane
Cell type enhanced (Respiratory ciliated cells, Endometrial ciliated cells)
Low immune cell specificity
Low cell line specificity
The functional gamma-secretase complex is composed of at least four polypeptides: a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PSENEN.